Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using monomethylated H3-K4 peptide as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 187nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 279nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate preincubated for 15 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of LSD1/FLAG-tagged CoREST (unknown origin) expressed in HEK293F cells using diMeK4H3(1 to 21 residues) as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of human N-terminal GST-tagged LSD1 expressed in Escherichia coli using ARTK (Me)-2QTARKSTGGKAPRKQLA as substrate/FLAG-tagged CoREST trans...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 352nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 554nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 642nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of LSD1/FLAG-tagged CoREST (unknown origin) expressed in HEK293F cells using diMeK4H3(1 to 21) as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair