Compile Data Set for Download or QSAR
maximum 50k data
Found 50 of ic50 data for polymerid = 50007369
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568523(CHEMBL4875015)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410785(CHEMBL5291155)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410784(CHEMBL5280566)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410789(CHEMBL5277056)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410788(CHEMBL5281376)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410786(CHEMBL5270114)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498143(CHEMBL3407602)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498128(CHEMBL3410944)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498142(CHEMBL3407601)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498137(CHEMBL3410941)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50410787(CHEMBL5270703)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity against FAAH in Wistar rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498150(CHEMBL3407599)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568517(CHEMBL4848459)
Affinity DataIC50:  90nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using monomethylated H3-K4 peptide as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498135(CHEMBL3407603)
Affinity DataIC50:  94nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498134(CHEMBL3407605)
Affinity DataIC50:  96nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498147(CHEMBL3407604)
Affinity DataIC50:  101nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50458056(CHEMBL4208031)
Affinity DataIC50:  107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50458056(CHEMBL4208031)
Affinity DataIC50:  107nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498141(CHEMBL3407597)
Affinity DataIC50:  118nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498130(CHEMBL3407600)
Affinity DataIC50:  121nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498140(CHEMBL3407596)
Affinity DataIC50:  123nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50458055(CHEMBL4214605)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498144(CHEMBL3407608)
Affinity DataIC50:  158nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498133(CHEMBL3407606)
Affinity DataIC50:  173nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498151(CHEMBL3407598)
Affinity DataIC50:  178nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498132(CHEMBL3407612)
Affinity DataIC50:  187nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498131(CHEMBL3407613)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498149(CHEMBL3407594)
Affinity DataIC50:  248nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498127(CHEMBL3407607)
Affinity DataIC50:  251nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498145(CHEMBL3407593)
Affinity DataIC50:  258nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498152(CHEMBL3407611)
Affinity DataIC50:  263nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498129(CHEMBL3407609)
Affinity DataIC50:  279nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50568518(CHEMBL4877195)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant human KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate preincubated for 15 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50548040(CHEMBL4791172)
Affinity DataIC50:  330nMAssay Description:Inhibition of LSD1/FLAG-tagged CoREST (unknown origin) expressed in HEK293F cells using diMeK4H3(1 to 21 residues) as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50610592(CHEMBL5272967)
Affinity DataIC50:  330nMAssay Description:Inhibition of human N-terminal GST-tagged LSD1 expressed in Escherichia coli using ARTK (Me)-2QTARKSTGGKAPRKQLA as substrate/FLAG-tagged CoREST trans...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498139(CHEMBL3407592)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498138(CHEMBL3410945)
Affinity DataIC50:  352nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498136(CHEMBL3410942)
Affinity DataIC50:  554nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498146(CHEMBL3407610)
Affinity DataIC50:  642nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498153(CHEMBL3407595)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498154(CHEMBL3407614)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498148(CHEMBL3410943)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant KDM1A/CoREST complex expressed in Escherichia coli using mono-methylated H3-K4 peptide containing 21 amino acids as s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50548040(CHEMBL4791172)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of LSD1/FLAG-tagged CoREST (unknown origin) expressed in HEK293F cells using diMeK4H3(1 to 21) as substrate preincubated for 5 mins follow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50446143(CHEMBL3108897)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST preincubated for 5 mins followed by ART-(N,N-dimethyl-K)-QTARKSTGGKAPRKQLA substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498660(CHEMBL1605826)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50498660(CHEMBL1605826)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1(Homo sapiens (Human))
Key Laboratory Of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50236898((1S,2R)-(+)-2-phenylcyclopropylamine | CHEMBL25799...)
Affinity DataIC50:  2.07E+4nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed